Malaysian jungle Tualang honey (TH) shows remarkable anti-cancer effects in modulating breast carcinogenesis. The results of the study, published in BMC Complementary and Alternative Medicine, found that TH efficiently induces apoptosis (cell death) in breast cancer cells while regulating various hematological parameters.
Fifty female Sprague-Dawley rats were grouped in one of five groups:
Group 0 — Control (healthy, normal rats)
Group 1 — Untreated rats
Group 2 — Received 0.2 g/kg body weight of TH
Group 3 — Received 1.0 g/kg body weight of TH
Group 4 — Received 2.0 h/kg body weight of TH
Rats in groups 1 to 4 were induced with 80 mg/kg of 1-methyl-1-nitrosourea (MNU).
Groups 2, 3, and 4 started their TH treatment one week after tumor induction. Treatment was continued for 120 days.
TH-treated rats displayed differences in: tumor progression (75.3 days compared to 51.5 days); tumor incidence (76.6 percent compared to 100 percent); multiplicity (2.5 tumor masses per rat compared to 4); and the size and weight of the tumor mass compared to the control and untreated groups.
Further, rats in TH treatment groups displayed higher pro-apoptotic proteins.
Authors of this study conclude that TH is a natural breast cancer treatment. Tualang honey modulates hematologic, estrogenic, and apoptotic activities in breast cancer models. Researchers noted that these effects were profound and should be further studied.

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